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It also comprises key residues that facilitate the GSH-based nucleophilic attack on the electrophilic substrate, leading to the formation of a thioether bond and the subsequent detoxification of the substrate

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[DOI] [PubMed] [Google Scholar] 45.Li J

234,235 In addition, Met is broken down by the Met cycle, in which Met adenosine transferase 2A (MAT2A) is upregulated and highly active in tumors

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