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Unlike native -MSH, which has a very short plasma half-life due to rapid enzymatic degradation, MT-1 incorporates a linear sequence modification that significantly extends its stability in biological matrices while preserving high-affinity binding at melanocortin receptors primarily MC1R, the receptor responsible for eumelanin synthesis in melanocytes

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Barbalho SM, Bosso H, Salzedas-Pescinini LM, de Alvares Goulart R

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Upregulation of peripubertal rat Leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine

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