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Supplementary Information Additional file 1: Materials and Methods

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Contextual Variables Published dosing patterns are influenced by factors such as: body weight of the research model species differences (rodent vs in-vitro systems) delivery method measurement endpoints (angiogenesis, fibroblast activity, inflammation markers, etc.) These variables limit direct comparison between studies

When a medication powder is reconstituted with bacteriostatic water, the benzyl alcohol preservative continues to protect the solution against microbial contamination