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Surgical treatment early in stage 1,2 can correct this sign

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In vitro and in vivo models, knockout or inhibition of GPX4 can rapidly induce severe lipid peroxidation, mitochondrial rupture, and typical ferroptosis phenotypes in chondrocytes, further reinforcing its core role in maintaining joint homeostasis (Sun S

Through high-throughput drug screening and single-cell genomic analysis, studies have found that HRAS mutations are associated with the sensitivity to certain drugs, such as cytarabine (124)
