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Preliminary findings from these studies suggest a tolerable oral dosage of approximately 100mg/kg in mice [1]

Identification, cloning, expression, and purification of three novel human calcium- independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

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Consequently, its rapid metabolism into active fragments and lack of systemic accumulation highlight a strong clearance profile, reducing the potential for peptide build-up or toxicity