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It is characterised by its selective interaction with NNMT (Nicotinamide-N-Methyltransferase) , an enzyme implicated in a range of metabolic and biochemical regulatory processes, making it a valuable reference compound for preclinical and in-vitro research programmes

Generally, NNMT activity or expression is significantly elevated in cancers, such as brain [68], lung [69], liver [70], kidney [71, 72], bladder [73], stomach [74, 75], pancreas [76], colon [77], and oral [78, 79] cancer but cancer cells usually have a significantly higher anaerobic metabolism rate than normal cells

Hydroxocobalamin 1mg/1ml Solution for Injection Summary of Product Characteristics

Retrieved 26 June 2021

Methylcobalamin is the active, naturally occurring form your body can use immediately supporting methylation, energy, and nerve health