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Apart from these, GSTs play a significant role in the developmental and physiological functions namely hormone biosynthesis, tyrosine degradation, and peroxide breakdown [17], stress signalling [18], nodule function [19], and non-catalytically acting as flavonoid-binding proteins [20]

Several microbial metabolites have been linked to CVD ( Figure 2 depicts how the inflammatory response influences the development of glucose intolerance, diabetes, and CVD ( Figure 2 Gut microbiota composition, diversity, and risk factors The bacterial composition, diversity, and abundance are highly influenced by genetic changes in the hosts genome, and by external variables such as the hosts lifestyle, diet, sanitation, health, and the use of antibiotics and probiotics ( Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria, Fusobacteria , and Verrucomicrobia , with the majority of the organisms in a healthy bacterial community being anaerobic population, as shown in Figure 3 (57, Figure 3 , several risk factors were put out as potential causes of intestinal dysbiosis

However, such drugs can have serious side effects (motor disorders like Parkinsons disease) and are not recommended for long-term use or as a substitute for benzodiazepines

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