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CYP3A4 and CYP3A5: the crucial roles in clinical drug metabolism and the significant implications of genetic polymorphisms

Aging is an inevitable process, but science continues to unlock new ways to slow its effects

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The authors reported modestly higher objective sleep efficiency and shorter sleep latency in the DSIP arm versus placebo, but subjective sleep-quality measures did not improve and the authors themselves concluded that short-term treatment of chronic insomnia with DSIP is not likely to be of major therapeutic benefit. That is the strongest controlled human sleep study in the literature, and its conclusion is negative to modest