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Over time, there are also potential concerns to consider: Skin thinning (atrophy) with prolonged use Worsening of symptoms after stopping treatment In some cases, a condition called topical steroid withdrawal , which may involve burning, stinging, or rebound flares after discontinuation Not everyone experiences these issues

10.1016/j.jbspin.2005.03.003 193 MundyC.YasudaT.KinumatsuT.YamaguchiY.IwamotoM.Enomoto-IwamotoM.et al (2011)

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However, we tried several values of V mean and V eff as well as replacing the ohmic formalism by the GHK formalism and every version of the model gave a qualitative synergy

Whichever route you take, success depends on ongoing medical support , nutrition advice , and healthy daily habits to maintain results long term