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Experimental findings indicate that the compound may trigger cellular mechanisms that release fatty acids from fat stores without significantly altering insulin or IGF-1 levels

Low incidences of seizures have been reported with oral doses in individuals with or without pre-existing seizure disorders.

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Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass

Larsen, N

In turn, phosphorylation of the adaptor proteins insulin receptor substrate 14 (IRS-14) and Shc leads to activation of the phosphatidyl inositol-3 kinase (PI3K), the mitogen-activated protein kinase (MAPK) and the 14-3-3 pathways (Baserga, 2000)