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In MCD (1015% fat (lard or soybean oil) and 4050% carbohydrates)-induced MASLD model within 48 weeks, the levels of several fibrosis-related targets, a-Sma , TGF-b1 , Col1a1 and Col3a1, were significantly increased

This timing aligns MOTS-c's AMPK activation with the metabolic demands of training

The response to treatment appeared to be stronger in women who received MSCs loaded on a collagen scaffold, a fibrillary network that helps retain the stem cells in the ovary

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doi: 10.1016/j.ajog.2008.06.094