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This is important because it suggests the anti-psoriatic activity can be localized to a specific portion of the larger protein, potentially allowing the development of small, targeted peptide therapeutics

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ID can impair mitochondrial function, reducing energy production and compromising cell function ( Iron is absorbed in the intestine in two forms: heme and non-heme iron

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While lacking confidence in an interaction does not preclude a genuine association, it highlights that no such interaction between these kinases and similarly structured nuclear receptors has been previously reported