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Duration of NFT-dependent increase in glutathione levels To determine the duration and the response of glutathione following withdrawal and re-addition of NFT, HepG2 cells were treated with NFT (20 M) for 48 h, followed by withdrawal of NFT for 24 h and a subsequent re-addition of NFT for an additional period of 24 h (Fig
[DOI] [PubMed] [Google Scholar] 84.Loh S.N
The pathogenesis involves a type IV hypersensitivity reaction where the drug acts as a hapten, binding to tubular cells and inducing a T-cell-mediated immune response

FIGURE 2 Table 1 Insulin-like growth factor-1 signaling pathway-targeting miRNAs

Sci Rep 12:5599

9( Z ),12( Z )-11( S )-HpODE is first produced and then rearranges into 13( R )-HpODE via a linoleoyl radical