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While berberine is safe for most people to use, there are some possible side effects, like abdominal discomfort, constipation, diarrhea and nausea

Lally et al

J Proteome Res 14:33223335

Potentially for small areas such as under the chin, the procedure may take 30 to 45 minutes

138.Weimbs T, Saville J, Kalantar-Zadeh K
Evangelista E, Lopez R, Barateau L, et al
