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PMID: 35247050 J Chromatogr B Analyt Technol Biomed Life Sci Simultaneous determination of choline, L-carnitine, betaine, trimethylamine, trimethylamine N-oxide, and creatinine in plasma, liver, and feces of hyperlipidemic rats by UHPLC-MS/MS

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This multi-pathway neurotransmitter support is a key reason why clinical evaluations of ALCAR consistently note improvements in mood and emotional resilience alongside cognitive gains

There were no differences in age, BMI, gender, HDRS-24 scores before treatment, treatment days and other demographic characteristics between the effective-treatment and ineffective-treatment groups, there was significant difference in the reduction rate of HDRS-24 scores and HDRS-24 scores after treatment between the two groups (Table 2)
