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10.1016/j.arr.2024.102517 132 LevakN.LehtisaloJ.ThunborgC.WestmanE.AndersenP.AndrieuS.et al (2024)

c , Mitochondrial GSH and GSSG abundance (top and middle panels) and total intracellular GSH levels in HEK-293T parental or SLC25A39 knockout cells expressing a vector control or SLC25A39 cDNA

The pathogenesis of ALD involves multiple interconnected aging-related processes, including oxidative stress, inflammation, and mitochondrial dysfunction, all of which are regulated by SIRT1, a key modulator of cellular stress responses (Ramirez et al., 2017)

Hydrogen peroxide has no charge and therefore, can cross biological membranes

The docking results with the lowest binding energies for the four diseases are shown in Fig

24: 101978 (read) 2020 Bellande K, Lalo A, Ligat L, Roujol D, Jamet E, Canut H (2020) Recombinant N- glycosylation isoforms of Legume lectins: production and purification from Nicotiana benthamiana leaves following RuBisCO depletion