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Importantly, low Se levels in pregnant women affect fetal growth and augment the risk of delivering a small-for-gestational age infant by reducing placental antioxidant defense, while low Se in the third trimester is thought to indicate increased demands by the placenta, an issue which requires further confirmation

The copper component contributes essential cofactor activity for enzymes involved in melanin synthesis and structural protein cross-linking, supporting both pigmentation and mechanical properties of hair fibers