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TMA is primarily formed in the gut through the enzymatic metabolism of certain dietary compounds present in foods such as peanuts, dairy products, liver, egg yolks, and other full-fat dietary items, which all characterized by high levels of choline and carnitine, being both important precursors of TMA and TMAO (Wu K

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Carnitine deficiency occurs in aberrations of carnitine regulation in disorders such as diabetes, sepsis, cardiomyopathy, malnutrition, cirrhosis, endocrine disorders and with aging

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Neurobiol Dis 38:259265 de Paula S, Vitola AS, Greggio S, de Paula D, Mello PB, Lubianca JM, Xavier LL, Fiori HH, Dacosta JC (2009) Hemispheric brain injury and behavioral deficits induced by severe neonatal hypoxia-ischemia in rats are not attenuated by intravenous administration of human umbilical cord blood cells

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