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Proline is important in cellular homeostasis (cell proliferation or cell death) and can act as a signaling molecule to modulate mitochondrial functions and trigger specific genes expression, which is essential for plant recovery from stresses 20

Oncogenesis 4 , e162 (2015)

In vivo experiments were performed in a rat model system, and these findings confirmed the conclusions previously drawn from experiments on human-derived cell lines (Tong et al., 2013

Studies have shown that the expression level of Nrf2 is directly related to the susceptibility to iron poisoning

and as a carbon source for biomass and energy production (Fig

Because it binds poorly to IGFBPs, it remains free and biologically active in circulation far longer than native IGF-1