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*Correspondence: Ke Chen, [email protected] Jia, [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Histological analysis Hematoxylin and Eosin (H&E) staining Paraffin-embedded skin sections were deparaffinized, rehydrated, stained with hematoxylin, differentiated in acid alcohol, neutralized in ammonia, and counterstained with eosin

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