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As a cytoprotective agent, mediating Roberts cytoprotection, it maintains endothelium integrity and has a particular angiomodulatory effect (Sikiric et al., 1993

Approval status (read carefully): elamipretide received FDA accelerated approval in September 2025 under the brand Forzinity but only for Barth syndrome (to improve muscle strength in patients weighing 30 kg), on a surrogate endpoint, with a confirmatory trial potentially required [3]

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