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It was noted that ERR inverse agonist XCT 790 has been shown to clear -synuclein aggregates in an autophagy-dependent, mTOR-independent manner, offering potential neuroprotective effects in Parkinsons disease models by enhancing autophagosome biogenesis [139]

Osswald, N

10.1038/s42255-024-01140-6 [DOI] [PMC free article] [PubMed] [Google Scholar] 10.Flannick J, Thorleifsson G, Beer NL et al (2014) Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

Palladino, E

The right hemisphere of the brain was snap-frozen in liquid nitrogen (LN 2 ) and stored at 80 C until subsequent biochemical analysis

COL5A1 signal peptide mutations interfere with protein secretion and cause classic EhlersDanlos syndrome
