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Orally administered GSH is not directly absorbed by the body because of its degradation by gastrointestinal peptidase

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MPO was expressed as ;g/g protein in biopsies

the other TCAs failed clinical trials for this indication, likely due to insufficient serotonergic activity

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These results support the notion that enhanced GST-mediated conjugation represents a key mechanism contributing to CF resistance in recurrent EC and highlight the potential value of evaluating multiple GST genes rather than a single marker