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Abbreviations APAP : Acetaminophen GJ : Gap-junction NAC : N-acetylcysteine GSH : Glutathione NAPQI : N-acetyl-p-benzoquinone imine ROS : Reactive oxygen species Nrf2 : Nuclear factor E2-related factor 2 Cx32 : Connexin 32 TTSP : Type II transmembrane serine protease HGF : Hepatocyte growth factor References Chiew AL, Isbister GK

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In the nab-paclitaxel monotherapy group, the mPFS and OS were 5.52 months (95% CI: 0.945.88) and 11.50 months (95% CI: 10.0213.57), respectively

In some cases, splenectomy has been efficacious in modifying the anemia, although hemolysis may continue as manifested by persistent reticulocytosis
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