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Archived from the original (PDF) on 17 July 2011

the silent information regulator 3 (sirtuin3) gene

Enhances Liver Function The lipotropic compounds help promote liver health by enhancing detoxification and fat processing

This is somewhat surprising, as the literature contains numerous examples of the ability of ascorbate to eliminate or mitigate the harmful effects of many types of xenobiotics with pro-oxidant properties 6466

the original rodent study used 5 mg/kg, which when scaled allometrically to human equivalents suggests doses in the 5-10 mg range for a 70 kg adult, though allometric scaling from mice to humans is an imprecise science

The E-isomer is predominant because it facilitates the formation of hydrogen bonds between the oxime and enol groups
