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Drug Targets 12 (4), 556562

U S A 107, 75567561

The investigators hypothesized that treatment with oral GABA, or a combination of GABA/GAD65-alum, would halt or slow the progression of new onset type 1 diabetes (T1DM) by some/all of the following mechanisms: 1) increasing endogenous insulin secretion, 2) suppression of glucagon release, 3) dampening the T-cell mediated autoimmune process

Given these cells are also CD4 + T cells like those studied by Ghergurovich et al., it is possible that production of these cytokines is impaired like their T h 1 counterparts