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AHK-Cu has been studied in this context for its possible contribution to enhancing VEGF signaling, which may in turn support fibroblast and endothelial cell activity

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By comparing the gene expression profiles of the skin microbiota in acne patients with the profiles from healthy individuals, the vitamin B 12 biosynthesis pathway in the skin bacterium Propionibacterium acnes turned out to be significantly down-regulated in acne patients

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