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Compared to GLP-1 Agonists: Weight management peptides like semaglutide and tirzepatide have demonstrated weight loss efficacy superior to AOD-9604 in clinical trials, but they also have distinct side effect profiles

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Loss of GSH synthesis resulted in a decreased expression of lipogenic enzymes, including SCD1

In chronic toxicology studies in rats (6 months) and cynomolgus monkeys (9 months), the potential toxicity of AOD9604 was assessed after daily oral gavage

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