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Metabolism Naloxone hydrochloride is metabolized in the liver, primarily by glucuronide conjugation, with naloxone-3-glucoronide as the major metabolite

Thompson W, Dawson RM

2024 January;113(1):E3-E4 | doi:10.12788/cutis.0933 PRACTICE POINTS Although tanning beds are arguably the most common and dangerous method used by patients to tan their skin, dermatologists should be aware of the other means by which patients may artificially increase skin pigmentation and the risks imposed by undertaking such practices

Reduced FH expression, and the consequent accumulation of fumarate in the kidney, may contribute to the decline of eGFR[192]

Goffart S, von Kleist-Retzow JC, Wiesner RJ

Central neural pathways for thermoregulation