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A standard blood test for vitamin B12 can be misleading, especially if you've been taking high-dose B12 supplements

for instance, exposure of astrocytes in cell culture to high levels of ROS induces transcription of genes responsible for synthesizing GSH (Gegg et al., 2003

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Still, most of that evidence comes from laboratory and animal models rather than large-scale human trials

Hann, J.B

Redox sensing by proteins: Oxidative modifications on cysteines and the consequent events [Research Support, Non-U.S