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(6) a wide range of free toxic compounds increase mitochondrial membrane's permeability, one of which is the presence of free fatty acids surrounding mitochondria

[12] Acetyl-CoA stabilization [edit] Carnitine plays a role in stabilizing acetyl-CoA and coenzyme A levels through the ability to receive or give an acetyl group

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

Patients normally respond to pharmacological doses of oral L-carnitine, particularly if supplementation is implemented prior to organ damage [64]

Physiological functions of carnitine and carnitine transporters in the central nervous system 4, 6

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