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Therefore, melatonin may protect the aged heart against ischemia/reperfusion injury by inhibiting apoptosis and activating the sirtuin 3/FOXO1 signaling pathway (Jafari-Azad et al., 2021)

E N D Presentation Transcript GLUTATHIONE SYNTHESIS, EFECT OF NUTRITION ON REGULATORY CONTROL MECHANISM Mohammad Hanafi, MBBS (Syd).,dr.,MS.) Senior Lecturer in Biochemistry Medical Faculty Unair 1.Introducion Glutathione (-glutamylcysteinylglycine, GSH) is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor

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Thus, for some catabolic/hypercatabolic patients, the changes in glutamine concentration, especially in plasma, will not necessarily affect and suppress immune functions, and possibly no significant changes might be observed in data obtained from immune parameters and function, and mortality risk predictors, such as APACHE II or SAPS III

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Maggs, L., Cattaneo, G., Dal, A