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Science 297 , 20482051 (2002)

Causes of Poor Sleep: Stress, an overactive mind, hormonal imbalances, and underlying inflammation

Anaphylactic shock and death have been reported

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Abstract The prevalence of hypogonadism is an increasing problem that affects increasingly more men of reproductive age

Moreover, despite the relief opioid drugs can provide for acute clinical and experimental pain (Wanigasekera et al., 2012), psychosocial stress (Bershad et al., 2015, 2018), certain depressive symptoms (Pecia et al., 2018), and feelings of breathlessness (Hayen et al., 2017), opioid blockade does not consistently increase the aversiveness of experimental pain (Anderson et al., 2002