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ncr-2(0) mutants displayed increased cholesterol levels compared with N2 animals (Fig S4A and B)

It does so by adding the situations of serotonin and dopamine, two neurotransmitters that are linked to passions of well- being and happiness

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It is tempting to speculate that a related pathway involving lipases and lipid chaperones may activate NHR-49 via a different lipid ligand to achieve longevity in the glp-1 and other contexts