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The rate constants from our deglutathionylation assays between 6.4 10 4 and 1.4 10 6 M 1 s 1 are very similar to the rate constants for PfGrx or plant and mammalian glutaredoxins from discontinuous or coupled enzymatic assays with other high and low molecular weight GSSR substrates (Table 1) 9,11,14,19 , thus confirming our assay as an alternative reliable method for the direct analysis of enzyme-catalyzed deglutathionylations

doi: 10.5551/jat.RV17020 170 NadraIMasonJCPhilippidisPFloreyOSmytheCDMcCarthyGMet al

GLP-1RAs such as CNTO3649 and exendin-4 reduced hepatic steatosis and lowered hepatic triglyceride, cholesterol, and phospholipid contents in HFD-fed APOE*3-Leiden transgenic mice [27]

GH secretagogues / longevity: 6-12 weeks

Edinburgh Churchill Livingstone, Elsevier

European Spine Journal, 18 , 18431850