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In a Drosophila model of HD, changes in the expression of clock genes, including Period and Timeless genes, were observed

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Cells were then incubated with STEMdiff Endoderm basal medium with 1X supplement CJ on days 1-3, with medium replenished daily

This feature renders cancer cells more sensitive to external stimuli that further increase the production of ROS 145,146,147 , and, as schematically summarized in Table 1, an increasing number of therapeutic strategies are being developed to elevate ROS levels to overwhelm the redox adaptation of the same cells, inducing oxidative stress incompatible with cellular life 148,149,150,151 (Fig

GSH is a known radical scavenger that decreases the number of free radicals available to sustain the polymerization cycle [11]