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Magnesium ions also aid stress tolerance, particularly against abiotic stressors, by competing with other cations such as aluminum (Al), which can trigger antioxidant defenses and modulate the expression of stress-responsive genes, including those encoding HSPs, SOD, CAT, LEA proteins, and dehydrins (Boaretto et al., 2020

However, there are still some challenges

A., Renner, M., Martin, C

Although suicidal and vital NETosis share notable common mechanisms among their key steps, including NET assembly and release, they lead to vastly different outcomes for neutrophils

Many of these have different storage requirements, varying expiration dates and limited shelf lives
