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The data were processed using the program XDS 42 and the structures were solved by molecular replacement using the program PHASER 43 with the structure of tynorphin bound hDPP III (1726) as search model

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A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure

Administered 1 mL of vitamin B12 IM into the right deltoid