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Sep 30 2022;12(10)doi:10.3390/diagnostics12102374

Such phosphorylation leads to the blockade of the tyrosine residues in IRSs, to which the insulin and IGF-1 receptors phosphorylate to activate IRSs and consequently commence the signalling cascade [185, 192], as comprehensively discussed above

and Smith, V.J., Biochem

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