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Its also very common to experience side effects up to half of users do including symptoms like nausea, constipation, bloating, dehydration, fatigue, and muscle loss

Mean reductions from baseline in A1C were generally greater for patients with higher baseline A1C values

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If anxiety appears as drug levels decline, it could represent a withdrawal-like phenomenon between doses, though this is poorly studied for tirzepatide

The study followed 132,551 people taking GLP-1 medication and 201,136 people taking sulfonylurea for 3 years to treat diabetes