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Valproyl metabolites trap mitochondrial CoA which leads to decreased ATP production, further depleting carnitine since ATP is needed for the carnitine transporter to work

Wertz K

Dussinger, Diane D

Aging Cell 10 , 980990 (2011)

Efectes fisiolgics [modifica] Efectes en la massa ssia [modifica] Amb el pas dels anys, en l'sser hum, la concentraci de carnitina a les cllules disminueix, afectant al metabolisme dels cids grassos de diverses maneres