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The MT superfamily combines a large variety of small Cys-rich proteins that have the ability to coordinate various transition metal ions, including Zn 2+ , Cd 2+ , and Cu + (Freisinger, 2011)

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These observations, in turn, reflect the fact that defective sperm function is frequently associated with the retention of excess residual cytoplasm as a result of impaired cytoplasmic extrusion during spermiogenesis

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TABLE 1 Characteristics of the intervertebral disc microenvironment under physiological and degenerative conditions

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