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Bmal1 deficiency can lead to genomic instability, increased oxidative stress, and cell cycle imbalance, thereby promoting cancer development and accelerating aging through its capacity to enhance mTORC1 activity (Khapre et al., 2014a)

Benzhydrocodone/APAP use with benzodiazepines or other CNS depressants can cause sedation, respiratory depression, coma or death

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In summary, uncovering a role for Epo in the regulation of the ventilatory response to hypoxia and/or hypercapnia as well as ventilatory instability will open new avenues in the field of control of breathing in the pathological setting of SA

doi: 10.3748/wjg.v23.i1.76 [DOI] [PMC free article] [PubMed] [Google Scholar] 70

& Peebles, R