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doi: 10.1007/s12094-008-0171-3

The protein CDC42-165aa, encoded by circular RNA circCDC42, inhibits CDC42 GTPase activity, thereby activating the Pyrin inflammasome and leading to pyroptosis of alveolar macrophages in Klebsiella pneumoniae infection, which exacerbates lung injury (259)

Sauna Therapy: Regular sauna usage can encourage detoxification, diminish stress, and improve overall well-being (10)

These correlations were more significant in the mouse model compared with the human cohort, likely due to the advanced disease stage of the human liver specimens and the hepatic fat loss commonly seen in advanced fibrotic MASH 56

Available from: Seo IH, Lee YJ

Pharmacogenomics in drug metabolism