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Gestational Ketogenic Diet Programs Brain Structure and Susceptibility to Depression & Anxiety in the Adult Mouse Offspring

Eventually, the proposed mutualistic relationship exacerbates epithelial damage and promotes a protumorigenic microenvironment

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a Values are mean SEM

The observations in preclinical studies have been supported by phase I and II clinical trials, where pharmacological doses of parenteral ascorbate demonstrated safety and chemotherapeutic efficacy in prolonging life span and improving quality of life [78, 85]