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These multidimensional factors spanning mitochondrial metabolism, cellular aging, metabolic function, and childhood trauma provided more detailed signatures to predict longitudinal changes in depression severity than each individual factor alone

conducted a single-center, randomized, double-blind, controlled trial with an LOE of 2b and 48 controls receiving 4 g of LC or placebo daily

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2011;3 doi: 10.1186/1758-5996-3-31