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First, we used adult NestinCreER T2 ;Rosa-LoxP-STOP-LoxP-EYFP reporter mice to show that two weeks of TAM chow and 5 d of injections led to LoxP recombination in a similar phenotypic population of neural stem and progenitor cells (NSPCs) in the adult dentate gyrus

PMID 25195560

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They work to the extent they work at all only inside a program that is doing the actual work

None of it is a prescription, a treatment recommendation, or medical advice

Its utility shines brightest in studies specifically centered on reducing adipose tissue and improving body composition