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Mechanistically, BPC-157 promotes fibroblast activity, modulates the nitric oxide system, enhances angiogenesis through vascular-endothelial growth factor, downregulates proinflammatory cytokines, and stimulates collagen remodeling (Figure 1)
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2.2 Study inclusion and exclusion criteria Studies eligible for inclusion were peer-reviewed English journal articles, reviews, or meta-analyses published between 2020 and 2025
