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This metabolic shift is primarily driven by hypoxia-inducible factor-1 alpha (HIF-1) (137, 138),

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Thyroid: Off J Am Thyroid Assoc (2014) 24(11):16429

This is a non-negotiable safety rule in any lab environment

These results provide evidence for local alterations whereby mast cells contribute to the initiation of inflammatory arthritis and may be targeted in intervention strategies