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As of 2024, IgG Fc engineering as a strategy to prolong plasma half-life is used in approved therapeutics for diverse pathologies, including for instance neutralization of a virus (YTE containing
Furthermore, increased permeability of the intestine in patients with celiac disease may allow zonulin to reach basolateral EGFR receptors
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403 , 404 These health conditions, which disproportionately affect Black and Hispanic populations, are believed to explain much of the elevated risk of dementia among Black and Hispanic populations
doi: 10.1038/s41385-020-0262-1 [DOI] [PMC free article] [PubMed] [Google Scholar] 77.Rogliani P, Calzetta L, Capuani B, et al
